Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 10/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | JAK3 | P52333 | 4/20 | 0.32 |
| ▸ | KRAS | P01116 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807646 | 0.81 | KCNH2 (0.36) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL2723202 | 0.80 | KCNH2 (0.36) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL26637402 | 0.80 | KCNH2 (0.36) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL22118053 | 0.80 | KCNH2 (0.36) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL15826470 | 0.78 | KCNH2 (0.35) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL14773479 | 0.78 | CHRNB2 (0.37) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL12331138 | 0.78 | CHRNB2 (0.37) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| SCHEMBL14773537 | 0.78 | CHRNB2 (0.37) | SCN7AKCNH2SCN5ASCN9ASCN10A | |
| Trifluoroacetic Acid SCHEMBL20296403 | 0.77 | BIRC2 (0.36) | TEAD1SCN9ASCN10ABTKJAK3 | |
| Trifluoroacetic Acid SCHEMBL20296401 | 0.77 | BIRC2 (0.36) | TEAD1SCN9ASCN10ABTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073450-A | KRAS G12C Preparation and application of mutant protein inhibitor | 药雅科技(上海)有限公司 | 2022-09-20 | — | — | CN | disclosed |