Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17434345 | 0.90 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL1671641 | 0.88 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL29106302 | 0.88 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL6586277 | 0.87 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL6590271 | 0.84 | MEN1 (0.57) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL30879336 | 0.83 | ALDH1A1 (0.62) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17434190 | 0.82 | POLB (0.55) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL28302402 | 0.81 | ALDH1A1 (0.50) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL30701819 | 0.81 | ALDH1A1 (0.50) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL5118138 | 0.81 | POLB (0.61) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109012-A | Benzyl arylamine aldehyde dehydrogenase agonist, and synthesis method and application thereof | 中国人民解放军海军军医大学 | 2022-09-27 | — | — | CN | disclosed |