Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880330 | 1.00 | HTT (0.41) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL26457642 | 1.00 | HTT (0.41) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL25847565 | 0.86 | CTSS (0.40) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL17041300 | 0.85 | TSHR (0.43) | CTSKKMT2AMEN1MAPTATM | |
| SCHEMBL25472039 | 0.85 | HTT (0.56) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL1343848 | 0.85 | HTT (0.56) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL31048703 | 0.85 | HTT (0.56) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL31733639 | 0.85 | HTT (0.56) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL17041345 | 0.84 | PPARG (0.41) | HTTCTSKCTSSKMT2AMEN1 | |
| SCHEMBL15336461 | 0.84 | HTT (0.43) | HTTCTSKCTSSKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |