SCHEMBL29945959

SCHEMBL29945959

Cc1c(Br)cccc1[C@@H](C)N[S@@+]([O-])C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23525967 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL29945711 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL30454856 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL23525970 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL23526053 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL23526055 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL23525971 1.00 SOS1 (0.32) SOS1HTT
SCHEMBL14977275 0.86 HTT (0.42) HTT
SCHEMBL25472038 0.86 HTT (0.42) HTT
SCHEMBL28934653 0.86 HTT (0.42) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543450-A1 SALTS OF SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2025-04-30 EP disclosed
CN-119546304-A Salts of SOS1 inhibitors 米拉蒂治疗公司 2025-02-28 CN disclosed
CN-119462626-A SOS1 inhibitors 米拉蒂治疗股份有限公司 2025-02-18 CN disclosed
CN-115135315-B SOS1 inhibitors 米拉蒂治疗股份有限公司 2024-11-26 CN disclosed
WO-2023250165-A1 SALTS OF SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2023-12-28 WO disclosed
EP-4076418-A1 SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2022-10-26 EP disclosed
CN-115135315-A SOS1 inhibitors 米拉蒂治疗股份有限公司 2022-09-30 CN disclosed