Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 4/20 | 0.70 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26628296 | 0.82 | STIM1 (1.00) | STIM1ORAI1NOTUMOGT | |
| SCHEMBL29946096 | 0.82 | STIM1 (1.00) | STIM1ORAI1NOTUMOGT | |
| SCHEMBL29946184 | 0.78 | STIM1 (0.84) | STIM1ORAI1 | |
| SCHEMBL26628274 | 0.78 | STIM1 (0.84) | STIM1ORAI1 | |
| SCHEMBL26628290 | 0.77 | STIM1 (0.75) | STIM1ORAI1MEN1KMT2ALMNA | |
| SCHEMBL29946201 | 0.77 | STIM1 (0.75) | STIM1ORAI1MEN1KMT2ALMNA | |
| SCHEMBL29946195 | 0.76 | STIM1 (0.88) | STIM1ORAI1OGT | |
| SCHEMBL26628313 | 0.76 | STIM1 (0.88) | STIM1ORAI1OGT | |
| SCHEMBL12700430 | 0.73 | NOTUM (0.48) | NOTUMOGT | |
| SCHEMBL26803808 | 0.72 | STIM1 (0.57) | STIM1ORAI1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | disclosed |