Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946293 | 0.89 | PIK3CD (0.45) | HSD17B10PIK3CD | |
| Trifluoroacetic Acid SCHEMBL28864675 | 0.89 | HSD17B10 (0.36) | HSD17B10 | |
| SCHEMBL9208423 | 0.79 | HSD17B10 (0.47) | HSD17B10PIK3CDKDM4E | |
| Trifluoroacetic Acid SCHEMBL28956754 | 0.79 | PIK3CD (0.38) | HSD17B10PIK3CD | |
| SCHEMBL31537139 | 0.77 | GRIK1 (0.32) | PIK3CDKDM4ELMNARAB9A | |
| SCHEMBL14671158 | 0.76 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2L3MBTL1HSD11B1 | |
| SCHEMBL7289985 | 0.76 | POLB (0.49) | HSD17B10KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL15438887 | 0.76 | POLB (0.49) | HSD17B10KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL15447586 | 0.76 | POLB (0.49) | HSD17B10KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL8406208 | 0.76 | POLB (0.49) | HSD17B10KDM4ELMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371425-A | Nitrogen-containing heterocyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-114846004-B | Antimalarial drugs | 德克萨斯大学系统董事会 | 2024-10-11 | — | — | CN | disclosed |
| CN-118725014-A | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118702766-A | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118702767-A | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-112771038-B | Pyridazine derivatives as SMARCA2/4 degrading agents | 奥里吉恩发现科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-118451090-A | Amide antiviral compound | 海南先声药业有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-111954539-B | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118055933-A | Selective PARP1 inhibitors and uses thereof | 成都百裕制药股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114890989-B | HDAC8 degradation agent with nitrogenous derivative as Linker, preparation method and application thereof | 广东晨康生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117355508-A | Heterocyclic derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116854758-A | CD73 inhibitors | 欧瑞克制药公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-114929721-B | CD73 inhibitors | 欧瑞克制药公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |