Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.72 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.72 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595415 | 0.96 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL21903077 | 0.96 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL29744797 | 0.96 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29947007 | 0.91 | DDB1 (0.67) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL30830949 | 0.89 | DDB1 (0.64) | DDB1CRBNGPR119 | |
| SCHEMBL31091747 | 0.85 | DDB1 (0.65) | DDB1CRBNGPR119MAPT | |
| SCHEMBL21903076 | 0.83 | DDB1 (1.00) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL20595497 | 0.83 | DDB1 (1.00) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL23301516 | 0.82 | DDB1 (0.62) | DDB1CRBNGPR119MAPTNAMPT | |
| SCHEMBL24125822 | 0.82 | DDB1 (0.62) | DDB1CRBNGPR119MAPTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076450-A1 | ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR | C4 Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |