Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.64 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29744797 | 0.92 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL20595415 | 0.92 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL21903077 | 0.92 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL29947073 | 0.89 | DDB1 (0.72) | DDB1CRBNGPR119 | |
| Hydrochloric Acid SCHEMBL29947007 | 0.87 | DDB1 (0.67) | DDB1CRBNGPR119 | |
| SCHEMBL31726711 | 0.84 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL29680886 | 0.84 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL23301516 | 0.82 | DDB1 (0.62) | DDB1CRBNGPR119 | |
| SCHEMBL24125822 | 0.82 | DDB1 (0.62) | DDB1CRBNGPR119 | |
| SCHEMBL24125697 | 0.82 | DDB1 (0.62) | DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |