Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947240 | 0.83 | KDM4E (0.51) | KDM4ESTAT3HIF1ANR4A2CREBBP | |
| SCHEMBL311147 | 0.72 | MAPK1 (0.52) | KDM4EALDH1A1FGFR1 | |
| SCHEMBL3072756 | 0.72 | NR4A2 (0.49) | KDM4ENR4A2MAPTKMT2AALDH1A1 | |
| SCHEMBL31498285 | 0.71 | HTT (0.55) | NR4A2MAPTKMT2AALDH1A1EGLN1 | |
| SCHEMBL27801091 | 0.71 | LCK (0.42) | KDM4ENR4A2MAPTKMT2AALDH1A1 | |
| SCHEMBL12894984 | 0.69 | NR4A2 (0.52) | KDM4ENR4A2KMT2AEGLN1LMNA | |
| SCHEMBL28854075 | 0.69 | PIK3CB (0.45) | KDM4ENR4A2MAPTKMT2AALDH1A1 | |
| SCHEMBL4251187 | 0.68 | EGLN1 (0.50) | EGLN1LMNAYTHDC1 | |
| SCHEMBL6669514 | 0.68 | FGFR1 (0.61) | KDM4EALDH1A1THRBLMNAFGFR1 | |
| SCHEMBL498053 | 0.67 | KDM4E (1.00) | KDM4ESTAT3HIF1AFLT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |