Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398222 | 0.89 | L3MBTL1 (0.50) | YTHDC1L3MBTL1CYP11B1CYP11B2NR1H4 | |
| SCHEMBL23293667 | 0.85 | CYP11B1 (0.54) | EGLN1EGLN3TNFCYP11B1CYP11B2 | |
| SCHEMBL12894984 | 0.84 | NR4A2 (0.52) | EGLN1YTHDC1L3MBTL1LMNA | |
| SCHEMBL1081805 | 0.80 | EGLN1 (0.69) | EGLN1EGLN3TNFCYP11B1CYP11B2 | |
| SCHEMBL28440773 | 0.80 | CYP11B1 (0.48) | L3MBTL1TNFCYP11B1CYP11B2P2RX7 | |
| SCHEMBL28634932 | 0.80 | CYP17A1 (0.48) | EGLN1NR1H4LMNA | |
| SCHEMBL1080421 | 0.79 | EGLN3 (0.55) | EGLN1EGLN3YTHDC1L3MBTL1NR1H4 | |
| SCHEMBL1082082 | 0.79 | EGLN3 (0.52) | EGLN1EGLN3YTHDC1L3MBTL1NR1H4 | |
| SCHEMBL18038344 | 0.79 | KDM4E (0.43) | EGLN1L3MBTL1LMNA | |
| SCHEMBL27801091 | 0.78 | LCK (0.42) | EGLN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234220-B2 | Immunomodulatory compounds | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| US-20210284624-A1 | IMMUNOMODULATORY COMPOUNDS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210284624-A1 | IMMUNOMODULATORY COMPOUNDS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| CN-113166100-A | Immunomodulatory compounds | 达纳-法伯癌症研究所有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3814330-A1 | IMMUNOMODULATORY COMPOUNDS | Dana-Farber Cancer Institute, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| WO-2009134850-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284624-A1 | IMMUNOMODULATORY COMPOUNDS | CRBN, CD47, CD58 | EGLN1 2345/4885EGLN3 3226/4885YTHDC1 4525/4885 |
| US-12234220-B2 | Immunomodulatory compounds | CRBN, CD47, CD58 | EGLN1 2345/4885EGLN3 3226/4885YTHDC1 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.