Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.54 |
| ▸ | GSK3A | P49840 | 6/20 | 0.54 |
| ▸ | GSK3B | P49841 | 6/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.54 |
| ▸ | PRKACA | P17612 | 5/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 4/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.54 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.54 |
| ▸ | CLK2 | P49760 | 4/20 | 0.54 |
| ▸ | MAP4K2 | Q12851 | 4/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.54 |
| ▸ | FLT1 | P17948 | 3/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15319514 | 0.88 | DAPK3 (0.51) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL22777777 | 0.74 | PLK4 (0.47) | PIM1GSK3AGSK3BPRKACARPS6KA3 | |
| SCHEMBL14836012 | 0.73 | CHEK1 (0.47) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL29947391 | 0.72 | ABCG2 (0.37) | CDK5DYRK1AKDRROCK1CLK2 | |
| SCHEMBL19578701 | 0.70 | DAPK3 (0.43) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL28769185 | 0.70 | DAPK3 (0.76) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL29944203 | 0.70 | PIM1 (1.00) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL9230695 | 0.70 | PIM1 (1.00) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL15319398 | 0.70 | ICAM1 (0.55) | PIM1GSK3AGSK3BCDK5PRKACA | |
| SCHEMBL31533914 | 0.70 | ICAM1 (0.55) | PIM1GSK3AGSK3BCDK5PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-B | Morpholine derivative, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |