Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 8/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391958 | 1.00 | GLP1R (0.47) | GLP1RGRM5GRM1GPR119PDE10A | |
| SCHEMBL22932920 | 0.90 | GPR119 (0.47) | GRM5GRM1GPR119ELANE | |
| SCHEMBL24321922 | 0.89 | GRM1 (0.50) | GRM5GRM1GPR119 | |
| SCHEMBL30583878 | 0.89 | GRM1 (0.54) | GRM5GRM1GPR119 | |
| SCHEMBL30120528 | 0.88 | GLP1R (0.52) | GLP1RPDE10A | |
| SCHEMBL29668627 | 0.88 | GRM1 (0.49) | GLP1RGRM5GRM1GPR119 | |
| SCHEMBL24321526 | 0.88 | GRM1 (0.49) | GLP1RGRM5GRM1GPR119 | |
| SCHEMBL22933049 | 0.87 | GPR119 (0.44) | GLP1RGRM5GRM1GPR119ELANE | |
| SCHEMBL24498578 | 0.87 | GRM1 (0.46) | GRM5GRM1GPR119ELANE | |
| SCHEMBL29668677 | 0.87 | GPR119 (0.44) | GLP1RGRM5GRM1GPR119ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638670-A | Condensed imidazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-115244056-B | Condensed imidazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115867546-B | Salt and crystalline forms of GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-113801136-B | Imidazo heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-4157832-A1 | SALT AND CRYSTAL FORMS OF GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| CN-115867546-A | Salts and crystalline forms of GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115244056-A | Condensed imidazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-10-25 | — | — | CN | disclosed |