⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18706685 | 0.82 | EPHX1 (0.31) | — | |
| SCHEMBL21384633 | 0.74 | — | — | |
| SCHEMBL15579763 | 0.72 | — | — | |
| SCHEMBL12199677 | 0.72 | — | — | |
| SCHEMBL15579708 | 0.72 | — | — | |
| SCHEMBL12199694 | 0.72 | — | — | |
| SCHEMBL12199518 | 0.72 | — | — | |
| SCHEMBL15579739 | 0.72 | — | — | |
| SCHEMBL21381932 | 0.68 | MMP13 (0.45) | — | |
| SCHEMBL3706337 | 0.68 | SYK (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301468-A1 | FGFR3 INHIBITOR COMPOUNDS | Eli Lilly and Company (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187443-A1 | FGFR3 INHIBITOR COMPOUNDS | ELI LILLY AND COMPANY (US) | 2022-09-09 | — | — | WO | disclosed |