SCHEMBL29947633

SCHEMBL29947633

Oc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1-c1nc2ccccc2s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.59
KDM4E B2RXH2 10/20 0.59
RAB9A P51151 8/20 0.59
KMT2A Q03164 8/20 0.59
NPC1 O15118 7/20 0.59
MEN1 O00255 7/20 0.59
GAA P10253 6/20 0.59
SMN1; SMN2 Q16637 6/20 0.59
POLB P06746 4/20 0.59
APP P05067 3/20 0.59
HSD17B10 Q99714 3/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
CASP1 P29466 1/20 0.59
SNCA P37840 1/20 0.59
CASP7 P55210 1/20 0.59
NPSR1 Q6W5P4 2/20 0.52
GLA P06280 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2789647 1.00 MAPT (0.59) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL20150707 0.91 MAPT (0.63) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL2789607 0.90 KDM4E (0.68) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL30594621 0.88 APP (0.67) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL25288484 0.84 KDM4E (0.71) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL28159222 0.84 MAPT (0.60) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL2789897 0.84 MAPT (0.60) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL2787764 0.83 MAPT (0.63) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL2789035 0.83 KDM4E (0.63) MAPTKDM4ERAB9AKMT2ANPC1
SCHEMBL14195510 0.82 APP (0.69) MAPTKDM4ERAB9AKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209898-B Ratiometric fluorescent probe, preparation method thereof and application thereof in sulfite ion detection 华南理工大学 2022-10-25 CN claimed
CN-112209898-B Ratiometric fluorescent probe, preparation method thereof and application thereof in sulfite ion detection 华南理工大学 2022-10-25 CN disclosed