Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729405 | 1.00 | HTT (0.54) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL24729427 | 0.95 | RAB9A (0.53) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL29947329 | 0.95 | RAB9A (0.53) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL29947482 | 0.92 | KDM4E (0.50) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL24729518 | 0.92 | KDM4E (0.50) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL24729510 | 0.91 | MAPT (0.49) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL29947389 | 0.91 | MAPT (0.49) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL24729362 | 0.86 | KDM4E (0.61) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL29947469 | 0.86 | KDM4E (0.61) | HTTKDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL24729368 | 0.84 | HTT (0.61) | HTTKDM4EL3MBTL1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |