SCHEMBL29948101

SCHEMBL29948101

Clc1cc(-c2ccccc2)c(-c2ccccc2)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 2/20 0.50
CYP2A6 P11509 1/20 0.50
CSNK2A1 P68400 3/20 0.41
BACE1 P56817 1/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
AHR P35869 2/20 0.38
ESR2 Q92731 1/20 0.38
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL735086 0.83 ALDH1A1 (0.62) ALDH1A1MAPK1CYP2A6BACE1CRHBP
SCHEMBL29405259 0.83 ALDH1A1 (0.62) ALDH1A1MAPK1CYP2A6BACE1CRHBP
SCHEMBL24731021 0.82 MAPK1 (0.50) ALDH1A1MAPK1CYP2A6CSNK2A1BACE1
SCHEMBL22433028 0.79 ALDH1A1 (0.44) ALDH1A1MAPK1CYP2A6CSNK2A1AHR
SCHEMBL734059 0.78 ALDH1A1 (0.56) ALDH1A1MAPK1CYP2A6BACE1CRHBP
SCHEMBL2470342 0.78 ALDH1A1 (0.62) ALDH1A1MAPK1CYP2A6CSNK2A1BACE1
SCHEMBL30582700 0.77 ALDH1A1 (0.50) ALDH1A1MAPK1CYP2A6CSNK2A1BACE1
SCHEMBL18828880 0.76 ALDH1A1 (0.54) ALDH1A1MAPK1CYP2A6BACE1CRHBP
SCHEMBL29284828 0.75 ALDH1A1 (0.44) ALDH1A1MAPK1CYP2A6CSNK2A1CYP1A2
SCHEMBL12403015 0.74 ALDH1A1 (0.52) ALDH1A1MAPK1BACE1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022203245-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-09-29 WO disclosed