SCHEMBL29948168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23552505	1.00	PTGER4 (0.47)	PTGER4PKN1PKN2SIK1SIK2
	SCHEMBL23552506	0.91	PTGER4 (0.47)	PTGER4PKN1PKN2SIK1SIK2
	SCHEMBL29948140	0.91	PTGER4 (0.47)	PTGER4PKN1PKN2SIK1SIK2
	SCHEMBL23530087	0.89	ABL1 (0.41)	PTGER4PKN1PKN2L3MBTL1IDH1
	SCHEMBL29948181	0.85	PKN1 (0.47)	PTGER4PKN1PKN2IDH1PARP1
	SCHEMBL23552540	0.85	PKN1 (0.47)	PTGER4PKN1PKN2IDH1PARP1
	SCHEMBL29948124	0.85	PKN1 (0.40)	PTGER4PKN1PKN2IDH1KDM4E
	SCHEMBL23529392	0.85	PKN1 (0.40)	PTGER4PKN1PKN2IDH1KDM4E
	SCHEMBL25095233	0.83	ABL1 (0.43)	PTGER4PKN1PKN2L3MBTL1IDH1
	SCHEMBL29948211	0.83	ABL1 (0.43)	PTGER4PKN1PKN2L3MBTL1IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.