Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.65 |
| ▸ | CA2 | P00918 | 13/20 | 0.65 |
| ▸ | CA9 | Q16790 | 13/20 | 0.65 |
| ▸ | CA12 | O43570 | 12/20 | 0.65 |
| ▸ | CA7 | P43166 | 9/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 5/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053758 | 0.95 | CA1 (0.71) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28457987 | 0.86 | CA1 (0.74) | CA1CA2CA9CA12CA7 | |
| SCHEMBL12194874 | 0.85 | KDM4E (0.47) | CA1CA2CA9CA12CA7 | |
| SCHEMBL15223769 | 0.83 | KDM4E (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18876701 | 0.83 | CA12 (0.60) | CA1CA2CA9CA12CA7 | |
| SCHEMBL23536326 | 0.83 | KDM4E (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6362012 | 0.83 | AOC2 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18361753 | 0.83 | CA1 (0.56) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3611926 | 0.82 | KDM4E (0.61) | — | |
| SCHEMBL12703538 | 0.82 | KDM4E (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |