Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 20/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23390424 | 1.00 | TRPV4 (0.54) | TRPV4KCNH2TRPM8 | |
| SCHEMBL23424502 | 0.92 | TRPV4 (0.61) | TRPV4KCNH2TRPM8 | |
| SCHEMBL29949017 | 0.92 | TRPV4 (0.61) | TRPV4KCNH2TRPM8 | |
| SCHEMBL29948780 | 0.91 | TRPV4 (0.56) | TRPV4KCNH2TRPM8 | |
| SCHEMBL23390573 | 0.91 | TRPV4 (0.56) | TRPV4KCNH2TRPM8 | |
| SCHEMBL23613933 | 0.84 | TRPV4 (0.56) | TRPV4KCNH2 | |
| SCHEMBL29948879 | 0.83 | TRPV4 (0.67) | TRPV4KCNH2TRPM8 | |
| SCHEMBL23424606 | 0.83 | TRPV4 (0.67) | TRPV4KCNH2TRPM8 | |
| SCHEMBL23424526 | 0.83 | TRPV4 (0.63) | TRPV4KCNH2TRPM8 | |
| SCHEMBL29948946 | 0.83 | TRPV4 (0.63) | TRPV4KCNH2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061124-A1 | TRPV4 RECEPTOR LIGANDS | University of Utah Research Foundation (US) | 2022-09-28 | — | — | EP | disclosed |