SCHEMBL29948771

SCHEMBL29948771

B.CCCC(=O)ON(OC(=O)CCC)OC(=O)CCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
KDM6B O15054 1/20 0.39
KDM5C P41229 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
HDAC3 O15379 4/20 0.39
HDAC1 Q13547 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
FFAR3 O14843 3/20 0.39
TSHR P16473 2/20 0.38
HDAC6 Q9UBN7 1/20 0.35
LMNA P02545 3/20 0.33
CTSD P07339 1/20 0.33
DGKA P23743 1/20 0.33
BCL9 O00512 1/20 0.32
CTNNB1 P35222 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29948810 0.85 CES1 (0.46) ALDH1A1CES2CES1TSHRLMNA
SCHEMBL291621 0.79
SCHEMBL29139113 0.78 ALDH1A1 (0.39) ALDH1A1KDM6BKDM5CEGLN1PHF8
Hydrochloric Acid SCHEMBL519616 0.77 KDM6B (0.60) ALDH1A1CES2CES1KDM6BKDM5C
SCHEMBL17686889 0.77 ALDH1A1 (0.52) ALDH1A1CES2CES1KDM6BKDM5C
SCHEMBL28937863 0.77 ALDH1A1 (0.52) ALDH1A1CES2CES1KDM6BKDM5C
SCHEMBL2001795 0.77 ALDH1A1 (0.41) ALDH1A1CES2CES1KDM6BKDM5C
SCHEMBL8786935 0.75 ALDH1A1 (0.50) ALDH1A1CES2CES1KDM6BKDM5C
SCHEMBL4760570 0.75 ALDH1A1 (0.50) ALDH1A1CES2CES1KDM6BKDM5C
SCHEMBL17686900 0.75 ALDH1A1 (0.50) ALDH1A1CES2CES1KDM6BKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022194022-A1 METHOD FOR PREPARING NALBUPHINE SEBACATE AND INTERMEDIATE THEREOF 苏州恩华生物医药科技有限公司 2022-09-22 WO claimed
WO-2022194022-A1 METHOD FOR PREPARING NALBUPHINE SEBACATE AND INTERMEDIATE THEREOF 苏州恩华生物医药科技有限公司 2022-09-22 WO disclosed