Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693646 | 1.00 | NPC1 (0.55) | NPC1ALDH1A1HTTEGFRSMN1; SMN2 | |
| SCHEMBL1923392 | 1.00 | NPC1 (0.55) | NPC1ALDH1A1HTTEGFRSMN1; SMN2 | |
| SCHEMBL29948741 | 1.00 | NPC1 (0.55) | NPC1ALDH1A1HTTEGFRSMN1; SMN2 | |
| SCHEMBL6714575 | 0.87 | NPC1 (0.48) | NPC1ALDH1A1HTTEGFRSMN1; SMN2 | |
| SCHEMBL14459586 | 0.86 | NPC1 (0.47) | NPC1ALDH1A1HTTEGFRSMN1; SMN2 | |
| SCHEMBL8304743 | 0.85 | KMT2A (0.46) | NPC1ALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL5744771 | 0.83 | ALDH1A1 (0.52) | NPC1ALDH1A1HTTEGFRSMN1; SMN2 | |
| SCHEMBL30434880 | 0.83 | LCK (0.43) | NPC1ALDH1A1HTTEGFRLMNA | |
| SCHEMBL1923555 | 0.83 | LCK (0.43) | NPC1ALDH1A1HTTEGFRLMNA | |
| SCHEMBL30434727 | 0.83 | LCK (0.43) | NPC1ALDH1A1HTTEGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028577-A | Purification method of 2-chloro-N- (2-chloro-4-methylpyridin-3-yl) nicotinamide | 盐城迪赛诺制药有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-115028577-A | Purification method of 2-chloro-N- (2-chloro-4-methylpyridin-3-yl) nicotinamide | 盐城迪赛诺制药有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115028577-A | Purification method of 2-chloro-N- (2-chloro-4-methylpyridin-3-yl) nicotinamide | 盐城迪赛诺制药有限公司 | 2022-09-09 | — | — | CN | disclosed |