Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399698 | 0.70 | MAPT (0.57) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL14944881 | 0.69 | KDM4E (0.55) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| Hydrochloric Acid SCHEMBL25401492 | 0.69 | MAPT (0.55) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL3755874 | 0.69 | KDM4E (0.40) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL4678156 | 0.67 | KDM4E (0.52) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL762893 | 0.67 | KMT2A (0.56) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL2805013 | 0.67 | KDM4E (0.52) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL7718402 | 0.67 | KDM4E (0.52) | MAPTKDM4EHSD17B10HIF1AMEN1 | |
| SCHEMBL29194643 | 0.66 | PIK3CD (0.41) | KDM4ETSHRLMNA | |
| SCHEMBL13940123 | 0.66 | ALDH1A1 (0.49) | MAPTKDM4EHSD17B10HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200162-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACECION PHARMA APS (DK) | 2022-09-29 | — | — | WO | disclosed |