Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16459744 | 0.81 | ACHE (0.70) | ACHEALDH2BCHEMEN1NPC1 | |
| SCHEMBL16473745 | 0.78 | ACHE (0.77) | ACHEALDH2BCHEMEN1NPC1 | |
| SCHEMBL16458944 | 0.75 | ACHE (0.73) | ACHEALDH2BCHEMEN1NPC1 | |
| SCHEMBL16458925 | 0.75 | ALDH2 (0.73) | ACHEALDH2BCHEMEN1NPC1 | |
| SCHEMBL12500900 | 0.73 | ACHE (1.00) | ACHEBCHE | |
| 7-Acetoxy-4',5-Dihydroxygenistein SCHEMBL10001910 | 0.72 | ALDH2 (0.75) | ACHEALDH2MEN1NPC1TP53 | |
| SCHEMBL14107144 | 0.72 | ALDH2 (0.75) | ACHEALDH2MEN1NPC1TP53 | |
| SCHEMBL16473741 | 0.71 | NPC1 (0.50) | ACHEALDH2MEN1NPC1TP53 | |
| SCHEMBL13911065 | 0.70 | ACHE (0.69) | ACHEALDH2BCHEMEN1NPC1 | |
| SCHEMBL31595515 | 0.70 | ALDH2 (0.76) | ACHEALDH2MEN1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250288672-A1 | HUMANIZED SYNTHETIC NOTCH RECEPTORS WITH AUGMENTED TRANSACTIVATION DOMAINS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-09-18 | — | — | US | disclosed |
| WO-2022204326-A1 | HUMANIZED SYNTHETIC NOTCH RECEPTORS WITH AUGMENTED TRANSACTIVATION DOMAINS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-09-29 | — | — | WO | disclosed |