Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18211318 | 1.00 | PNMT (0.56) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL25853626 | 1.00 | PNMT (0.56) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL16421362 | 1.00 | PNMT (0.56) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL20812100 | 0.88 | PNMT (0.42) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL20738451 | 0.88 | PNMT (0.42) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL6700680 | 0.86 | PNMT (0.53) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL25094181 | 0.84 | HDAC4 (0.42) | PNMTL3MBTL1 | |
| SCHEMBL10274869 | 0.84 | PNMT (0.53) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL24779791 | 0.84 | PNMT (0.53) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL25894263 | 0.84 | PNMT (0.53) | PNMTHTR2AHTR2CHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561247-A | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4313973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200162-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACECION PHARMA APS (DK) | 2022-09-29 | — | — | WO | disclosed |