SCHEMBL29949260

SCHEMBL29949260

Brc1ccc2c(c1)Cc1cc(Br)ccc1O2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.58
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
LMNA P02545 2/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
BLM P54132 1/20 0.42
METAP1 P53582 1/20 0.38
CA2 P00918 2/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
TDP2 O95551 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
SLC6A4 P31645 1/20 0.37
PNMT P11086 1/20 0.36
ASIC3 Q9UHC3 1/20 0.36
CA1 P00915 1/20 0.36
CA4 P22748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8184368 1.00 AHR (0.58) AHRMAOAMAOBLMNAMAPT
SCHEMBL11814041 0.90 MAOA (0.65) AHRMAOAMAOBLMNAMAPT
SCHEMBL16518351 0.88 AHR (0.47) AHRMAOAMAOBLMNAMAPT
SCHEMBL620562 0.86 AHR (0.58) AHRMAOAMAOBLMNAMAPT
SCHEMBL3335046 0.83 MAOA (0.45) AHRMAOAMAOBMETAP1TDP2
SCHEMBL571224 0.81 BACE1 (0.44) AHRMAOAMAOBLMNAMAPT
SCHEMBL16527632 0.81 AHR (0.40) AHRMAOAMAOBLMNAMAPT
SCHEMBL16527570 0.81 AHR (0.40) AHRMAOAMAOBMAPTCA2
SCHEMBL23447545 0.80 AHR (0.39) AHRMAOAMAOBLMNAMAPT
SCHEMBL12682940 0.80 AHR (0.47) AHRMAOAMAOBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112358473-B Heteroanthracene derivative and application thereof and organic electroluminescent device 武汉尚赛光电科技有限公司 2022-09-27 CN disclosed