Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120210 | 1.00 | NPY5R (0.45) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL29949115 | 0.96 | NPY5R (0.46) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL23120186 | 0.96 | NPY5R (0.46) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL23132196 | 0.93 | NPY5R (0.49) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL15773490 | 0.88 | CHEK2 (0.43) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL24501022 | 0.87 | NPC1 (0.50) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL21298554 | 0.86 | NPY5R (0.53) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL23131911 | 0.86 | NPY5R (0.54) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL23131914 | 0.84 | PDE10A (0.44) | NPY5RNPC1GAARAB9AKDM4E | |
| SCHEMBL23948708 | 0.83 | NPY5R (0.50) | NPY5RNPC1GAARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031549-A1 | PERI-CONDENSED HETEROCYCLIC COMPOUNDS AS MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2022-07-27 | — | — | EP | disclosed |