Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23132039 | 0.88 | NPY5R (0.43) | PDE10ANPY5RNPC1RAB9AGAA | |
| SCHEMBL23120186 | 0.87 | NPY5R (0.46) | PDE10ANPY5RNPC1RAB9AGAA | |
| SCHEMBL29949115 | 0.87 | NPY5R (0.46) | PDE10ANPY5RNPC1RAB9AGAA | |
| SCHEMBL10246753 | 0.84 | MEN1 (0.41) | NPY5RPTGER4HPGDKDM4EALDH1A1 | |
| SCHEMBL23120210 | 0.84 | NPY5R (0.45) | PDE10ANPY5RNPC1RAB9AGAA | |
| SCHEMBL29949312 | 0.84 | NPY5R (0.45) | PDE10ANPY5RNPC1RAB9AGAA | |
| SCHEMBL23132196 | 0.83 | NPY5R (0.49) | NPY5RNPC1RAB9AGAACHEK2 | |
| SCHEMBL11998330 | 0.83 | NPY5R (0.39) | NPY5RPTGER4HPGDKDM4EALDH1A1 | |
| SCHEMBL15197803 | 0.83 | TSPO (0.42) | NPY5RPTGER4HPGDKDM4EALDH1A1 | |
| SCHEMBL21965202 | 0.83 | TSPO (0.42) | NPY5RPTGER4HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220384735-A1 | PERI-CONDENSED HETEROCYCLIC COMPOUNDS AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-12-01 | — | — | US | disclosed |
| WO-2021053046-A1 | PERI-CONDENSED HETEROCYCLIC COMPOUNDS AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220384735-A1 | PERI-CONDENSED HETEROCYCLIC COMPOUNDS AS MATERIALS FOR ELECTRONIC DEVICES | KCNH1, NES, KCNC1 | PDE10A 2957/4885NPY5R 3702/4885NPC1 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.