Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 5/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103318 | 1.00 | DDB1 (0.52) | DDB1CRBNMAPK1NAMPTGLS | |
| SCHEMBL9913536 | 0.88 | ESR2 (0.52) | DDB1CRBNMAPK1NAMPTESR2 | |
| SCHEMBL5774734 | 0.88 | UCHL1 (0.53) | DDB1CRBNMAPK1NAMPTESR2 | |
| SCHEMBL29554603 | 0.88 | UCHL1 (0.53) | DDB1CRBNMAPK1NAMPTESR2 | |
| SCHEMBL23121488 | 0.88 | DDB1 (0.51) | DDB1CRBNMAPK1NAMPTGLS | |
| SCHEMBL22530386 | 0.88 | DDB1 (0.51) | DDB1CRBNMAPK1NAMPTGLS | |
| SCHEMBL15042246 | 0.87 | DDB1 (0.50) | DDB1CRBNMAPK1NAMPTGLS | |
| SCHEMBL15104421 | 0.87 | DDB1 (0.50) | DDB1CRBNMAPK1NAMPTGLS | |
| SCHEMBL15042391 | 0.87 | DDB1 (0.50) | DDB1CRBNMAPK1NAMPTGLS | |
| SCHEMBL15103216 | 0.87 | DDB1 (0.50) | DDB1CRBNMAPK1NAMPTGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115996907-A | Inhibitors of MLH1 and/or PMS2 for cancer treatment | 奈奥芬莱有限公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-4031184-A1 | FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES | Purdue Research Foundation (US) | 2022-07-27 | — | — | EP | disclosed |