SCHEMBL29949667

SCHEMBL29949667

Brc1ccc2c(c1)Sc1ccc(-c3cccc(-c4ccccc4)c3)cc1S2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.48
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ESR1 P03372 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
MAOA P21397 1/20 0.35
KMO O15229 1/20 0.35
ACMSD Q8TDX5 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28518065 1.00 ALDH1A1 (0.48) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL28521784 0.96 ALDH1A1 (0.52) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL29949443 0.87 ALDH1A1 (0.43) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL28525478 0.87 ALDH1A1 (0.43) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL28508462 0.87 CYP2A6 (0.48) ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A
SCHEMBL29949479 0.87 CYP2A6 (0.48) ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A
SCHEMBL9508981 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL9511405 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL29949394 0.81 ALDH1A1 (0.39) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL29949483 0.81 MAPK1 (0.39) ALDH1A1MAPK1GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112358473-B Heteroanthracene derivative and application thereof and organic electroluminescent device 武汉尚赛光电科技有限公司 2022-09-27 CN disclosed