Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 14/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.68 |
| ▸ | ABL1 | P00519 | 3/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188431 | 0.88 | PIK3CG (0.70) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL1303667 | 0.88 | PIK3CD (0.65) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL1303474 | 0.87 | PIK3CG (0.56) | PIK3CGPIK3CAABL1PIK3CDMTOR | |
| SCHEMBL1303014 | 0.86 | PIK3CG (0.54) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL1303423 | 0.82 | PIK3CG (0.47) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL1304043 | 0.82 | RAB9A (0.47) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL1304344 | 0.81 | PIK3CD (0.70) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL13188712 | 0.81 | PIK3CG (0.75) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL13188214 | 0.80 | PIK3CG (0.69) | PIK3CGPIK3CAABL1PIK3CDAKT1 | |
| SCHEMBL13188934 | 0.80 | PIK3CG (0.69) | PIK3CGPIK3CAABL1PIK3CDAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197682-A1 | Organic Compounds | NOVARTIS AG | 2010-08-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197682-A1 | Organic Compounds | PIK3CA, PI4KA, PI4KB | PIK3CG 11/4885PIK3CA 1/4885ABL1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.