Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.57 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.54 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.51 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.51 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Melibiose SCHEMBL18398874 | 0.95 | GAA (0.56) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL5793535 | 0.92 | GAA (0.65) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL8325931 | 0.92 | GAA (0.65) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL20315376 | 0.92 | GAA (0.65) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL9317257 | 0.92 | CD209 (0.65) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL11265985 | 0.92 | LGALS3 (0.63) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL12990218 | 0.91 | CD209 (0.64) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL12990264 | 0.91 | CD209 (0.64) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL29777515 | 0.91 | CD209 (0.64) | GAACDK1CCNB1CD209LGALS8 | |
| SCHEMBL12989798 | 0.91 | CD209 (0.64) | GAACDK1CCNB1CD209LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789316-B | Compositions and methods for treating lysosomal storage disorders and disorders characterized by lysosomal dysfunction | 贝勒医学院 | 2022-09-27 | — | — | CN | disclosed |