SCHEMBL2995044

SCHEMBL2995044

CC/C=C\OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892357 1.00
SCHEMBL892356 1.00
SCHEMBL1407388 0.78
SCHEMBL8052611 0.78
SCHEMBL1407387 0.78
Water SCHEMBL5684260 0.78 TRPA1 (0.30)
SCHEMBL295389 0.75
SCHEMBL4408868 0.75
SCHEMBL14330321 0.75
SCHEMBL11037332 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10874957-B2 Methods for desalinating aqueous compositions through hetero-azeotropic distillation SAUDI ARABIAN OIL COMPANY (SA) 2020-12-29 US claimed
US-20200230519-A1 SYSTEMS AND METHODS FOR DESALINATING AQUEOUS COMPOSITIONS THROUGH HETERO-AZEOTROPIC DISTILLATION SAUDI ARABIAN OIL COMPANY (SA) 2020-07-23 US claimed
US-11253792-B2 Systems for desalinating aqueous compositions through hetero-azeotropic distillation SAUDI ARABIAN OIL COMPANY (SA) 2022-02-22 US disclosed
US-20210060454-A1 SYSTEMS AND METHODS FOR DESALINATING AQUEOUS COMPOSITIONS THROUGH HETERO-AZEOTROPIC DISTILLATION SAUDI ARABIAN OIL COMPANY (SA) 2021-03-04 US disclosed
US-10874957-B2 Methods for desalinating aqueous compositions through hetero-azeotropic distillation SAUDI ARABIAN OIL COMPANY (SA) 2020-12-29 US disclosed
EP-3705477-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Vertex Pharmaceuticals Incorporated (US) 2020-09-09 EP disclosed
US-20200230519-A1 SYSTEMS AND METHODS FOR DESALINATING AQUEOUS COMPOSITIONS THROUGH HETERO-AZEOTROPIC DISTILLATION SAUDI ARABIAN OIL COMPANY (SA) 2020-07-23 US disclosed
EP-3216787-B1 INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMA (US) 2020-02-19 EP disclosed
EP-3216787-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Vertex Pharmaceuticals Incorporated (US) 2017-09-13 EP disclosed
US-9096608-B2 Pharmaceutically active pyrazolo-triazine derivatives LEAD DISCOVERY CENTER GMBH (DE) 2015-08-04 US disclosed
US-9096608-B2 Pharmaceutically active pyrazolo-triazine derivatives LEAD DISCOVERY CENTER GMBH (DE) 2015-08-04 US disclosed
US-20140343098-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED (US) 2014-11-20 US disclosed
US-20140073653-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2014-03-13 US disclosed
WO-2013097947-A1 PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-07-04 WO disclosed
EP-2231671-B1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2013-04-24 EP disclosed
US-20130035327-A1 Modulators of ATP-Binding Cassette Transporters VERTEX PHARMACEUTICALS INCORPORATED 2013-02-07 US disclosed
US-20100178380-A1 Synthesis and applications of 2-OXO-4-methylthiobutyric acid, its salts and its derivatives ADISSEO IRELAND LIMITED (IE) 2010-07-15 US disclosed
US-7662997-B2 Synthesis and applications of 2-oxo-4-methylthiobutyric acid, its salts and its derivatives ADISSEO IRELAND LIMITED (IE) 2010-02-16 US disclosed
US-20080069920-A1 Synthesis and Applications of 2-Oxo-4-Methylthiobutyric Acid, Its Salts and Its Derivatives ADISSEO IRELAND LIMITED (IE) 2008-03-20 US disclosed
US-7186709-B2 Subjecting a vinyl ethers and an unsaturated ketoester to suitable conditions to generate a scaffold having the core dihydropyrancarboxamide or dihydropyrancarboxylic ester or acid; anticarcinogenic agents PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-03-06 US disclosed