Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
| ▸ | PDE1A | P54750 | 6/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 6/20 | 0.37 |
| ▸ | PDE9A | O76083 | 5/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27028803 | 1.00 | PDE4D (0.52) | PDE4DPDE1APDE1BPDE1CPDE9A | |
| SCHEMBL17258831 | 0.76 | RXRA (0.45) | PDE4DPDE1APDE1BPDE1CPDE9A | |
| SCHEMBL3432421 | 0.73 | PDE2A (0.38) | PDE4D | |
| SCHEMBL16059106 | 0.72 | GRM1 (0.41) | PDE4DPDE1APDE1BPDE1CPDE9A | |
| SCHEMBL24851273 | 0.70 | PDE4D (0.44) | PDE4DPDE9AGRM1SCD | |
| SCHEMBL31051054 | 0.70 | PDE10A (0.42) | PDE4DPDE1APDE1BPDE1CPDE9A | |
| SCHEMBL30596250 | 0.70 | PDE4D (1.00) | PDE4DPDE1APDE1BPDE1CPDE9A | |
| SCHEMBL29950623 | 0.69 | — | — | |
| SCHEMBL16505774 | 0.69 | PDE4D (0.44) | PDE4DPDE1APDE1BPDE1C | |
| SCHEMBL30691989 | 0.69 | PDE4D (0.41) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308563-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321055-A | Modulators of STING (interferon gene stimulators) | 辉瑞公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022195462-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2022-09-22 | — | — | WO | disclosed |