SCHEMBL2995057

SCHEMBL2995057

CC(CC1CCCc2ccccc21)C1CCCc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.46
CYP19A1 P11511 1/20 0.46
TBXAS1 P24557 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549328 0.84 IDO1 (0.44) SIGMAR1
SCHEMBL6541484 0.83 PRCP (0.53) CYP19A1TBXAS1
SCHEMBL14632819 0.81 CYP19A1 (0.45) CYP19A1TBXAS1
SCHEMBL2094512 0.80 IDO1 (0.44) SIGMAR1
SCHEMBL3296406 0.80 IDO1 (0.49)
SCHEMBL3000155 0.80 IDO1 (0.49)
SCHEMBL2995330 0.78 CHRM1 (0.43) CYP19A1TBXAS1
SCHEMBL15540606 0.77 IDO1 (0.50)
SCHEMBL5541899 0.77 CYP19A1 (0.54) SIGMAR1CYP19A1TBXAS1
SCHEMBL4081534 0.77 IDO1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed