SCHEMBL2995330

SCHEMBL2995330

CC(CC1CCCc2ccccc21)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.43
DRD2 P14416 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
CHRM3 P20309 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
ADRA1A P35348 1/20 0.43
HRH1 P35367 1/20 0.43
DRD3 P35462 1/20 0.43
KCNH2 Q12809 1/20 0.43
CYP19A1 P11511 1/20 0.43
TBXAS1 P24557 1/20 0.43
PDPK1 O15530 1/20 0.43
IDO1 P14902 1/20 0.41
PRCP P42785 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6541484 0.83 PRCP (0.53) CHRM1DRD2ADRA2BADRA2CCHRM3
SCHEMBL14632819 0.81 CYP19A1 (0.45) CYP19A1TBXAS1PDPK1IDO1PRCP
SCHEMBL2995057 0.78 SIGMAR1 (0.46) CYP19A1TBXAS1
SCHEMBL6252829 0.77 KMT2A (0.51) ADRA2BADRA2CADRA1A
SCHEMBL30129841 0.76 CYP19A1 (0.49) CYP19A1TBXAS1IDO1
SCHEMBL22721447 0.76 CYP19A1 (0.49) CYP19A1TBXAS1IDO1
SCHEMBL598590 0.76 CYP19A1 (0.49) CYP19A1TBXAS1IDO1
SCHEMBL12000673 0.76 PDPK1 (0.55) CYP19A1TBXAS1PDPK1
SCHEMBL7898127 0.76 IDO1 (0.52) CYP19A1TBXAS1IDO1
SCHEMBL29463951 0.74 IDO1 (0.44) IDO1PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62289533-A None JP disclosed
JP-62294628-A None JP disclosed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
JP-S62294628-A 1-(1-DECALYL)-2-CYCLOHEXYLPROPANE AND PRODUCTION THEREOF IDEMITSU KOSAN CO LTD 1987-12-22 JP disclosed
JP-S62289533-A 1-(1-TETRALYL)-2-PHENYLPROPANE, PRODUCTION THEREOF AND SYNTHETIC LUBRICATING OIL CONSISTING ESSENTIALLY OF SAID COMPOUND IDEMITSU KOSAN CO LTD 1987-12-16 JP disclosed