Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953834 | 1.00 | HPGD (0.43) | HPGDRECQLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13591135 | 0.78 | SLC6A4 (0.42) | SMN1; SMN2SLC18A3HRH3 | |
| SCHEMBL3840511 | 0.77 | HRH1 (0.42) | HPGDRECQLSMN1; SMN2HRH3 | |
| SCHEMBL11541050 | 0.75 | CYP19A1 (0.40) | SMN1; SMN2CHRM1 | |
| SCHEMBL11541056 | 0.75 | CYP19A1 (0.40) | SMN1; SMN2CHRM1 | |
| SCHEMBL11541062 | 0.75 | CYP19A1 (0.40) | SMN1; SMN2CHRM1 | |
| SCHEMBL8911524 | 0.75 | HPGD (0.55) | HPGDRECQLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7893289 | 0.74 | KDM4E (0.39) | NPC1SMN1; SMN2GLS | |
| Bromide SCHEMBL28182316 | 0.74 | HPGD (0.54) | HPGDRECQLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6400570 | 0.73 | HPGD (0.47) | HPGDRECQLNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108875-B | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by asymmetric catalysis of visible light, and preparation method and application thereof | 河南师范大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-115108875-A | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof | 河南师范大学 | 2022-09-27 | — | — | CN | disclosed |