SCHEMBL8911524

SCHEMBL8911524

c1ccc(CC2CCCCC2)nc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
RECQL P46063 1/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
HTR6 P50406 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.44
HRH3 Q9Y5N1 2/20 0.43
HRH1 P35367 1/20 0.42
CYP1A2 P05177 1/20 0.42
GRM5 P41594 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28182316 0.98 HPGD (0.54) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL1515203 0.94 HPGD (0.49) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL1515445 0.90 SMN1; SMN2 (0.48) HPGDRECQLSMN1; SMN2KDM4EHRH3
SCHEMBL6398671 0.87 HPGD (0.48) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL13208093 0.86 HRH3 (0.46) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL6400570 0.86 HPGD (0.47) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL6399683 0.84 HPGD (0.46) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL21078184 0.83 GBA1 (0.49) HPGDRECQLMEN1KMT2ANPC1
Piperidine SCHEMBL5689680 0.83 GBA1 (0.49) HPGDRECQLMEN1KMT2ANPC1
SCHEMBL29520963 0.81 GBA1 (0.55) SMN1; SMN2KDM4EHRH3HRH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129233-A1 ELECTROCHEMICAL REACTIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-06-26 WO claimed
CN-104903312-B RHO kinase inhibitor 卡德门企业有限公司 2019-01-29 CN claimed
CN-108802211-A The liquid phase detection method of related substances in a kind of Cefquinome sulfate breast injection 佛山市南海东方澳龙制药有限公司 2018-11-13 CN claimed
CN-108802212-A A kind of liquid phase detection method of lactation period Cefquinome sulfate breast injection related substances 佛山市南海东方澳龙制药有限公司 2018-11-13 CN claimed
CN-104511271-B A kind of molecular sieve, its manufacture method and its application 中国石油化工股份有限公司 2017-12-15 CN claimed
CN-105101996-A Treatment of ocular disorders KADMON CORP LLC 2015-11-25 CN claimed
CN-104903312-A RHO KINASE INHIBITORS KADMON CORP LLC 2015-09-09 CN claimed
WO-2025129233-A1 ELECTROCHEMICAL REACTIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-06-26 WO disclosed
CN-110461842-A FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB BIOPHARMA SPRL 2019-11-15 CN disclosed
CN-107108672-B Condensed five rings imdazole derivatives UCB生物制药私人有限公司 2019-11-08 CN disclosed
CN-110325522-A Liquid crystal compounds 默克专利股份有限公司 2019-10-11 CN disclosed
CN-109996791-A Single fluorination hexamethylene 默克专利股份有限公司 2019-07-09 CN disclosed
CN-109863226-A Nano capsule comprising liquid crystal media 默克专利股份有限公司 2019-06-07 CN disclosed
US-8415336-B2 Cyclic (aza)indolizinecarboxamides, their preparation and their use as pharmaceuticals SANOFI (FR) 2013-04-09 US disclosed
US-20120232081-A1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2012-09-13 US disclosed
US-20120142932-A1 METHOD FOR MANUFACTURING 4-(5-METHYLPYRIDIN-2-YLAMINO)PIPERIDINE-1-CARBOXYLIC ACID DERIVATIVE KYORIN PHARMACEUTICAL CO., LTD. (JP) 2012-06-07 US disclosed
EP-2459557-A1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2012-06-06 EP disclosed
CN-102471339-A Pyrrolopyridine inhibitors of kinases ABBOTT LAB 2012-05-23 CN disclosed
US-5622953-A DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG BASF AKTIENGESELLSCHAFT (DE) 1997-04-22 US disclosed
WO-1994022842-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142932-A1 METHOD FOR MANUFACTURING 4-(5-METHYLPYRIDIN-2-YLAMINO)PIPERIDINE-1-CARBOXYLIC ACID DERIVATIVE PAH, ALK, ADSL HPGD 2741/4885RECQL 4542/4885MEN1 2750/4885
US-20120232081-A1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS REN, ACE, PM20D2 HPGD 664/4885RECQL 152/4885MEN1 2274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.