Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699406 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL16857047 | 0.78 | TDP1 (0.40) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL18031330 | 0.78 | KDM4E (0.34) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL29882654 | 0.78 | CYP3A4 (0.42) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL5871099 | 0.78 | CYP3A4 (0.42) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL23181382 | 0.78 | CYP1A2 (0.34) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL4188467 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL19991156 | 0.78 | KDM4E (0.34) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL16463746 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL30431426 | 0.78 | KDM4E (0.34) | ALDH1A1TDP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308563-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321055-A | Modulators of STING (interferon gene stimulators) | 辉瑞公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116981459-A | Heterocyclic derivatives as janus kinase inhibitors | 奇斯药制品公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116348453-A | Heteroaromatic carboxamide compounds and uses thereof | 烨辉医药科技(上海)有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022228302-A1 | HETEROAROMATIC CARBOXAMIDE COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2022-11-03 | — | — | WO | disclosed |
| WO-2022195462-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2022-09-22 | — | — | WO | disclosed |