Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382486 | 0.75 | GPR119 (0.47) | GPR119GBA1KITKDM1AUSP30 | |
| SCHEMBL24154706 | 0.75 | GPR119 (0.47) | GPR119GBA1KITKDM1AUSP30 | |
| SCHEMBL28369668 | 0.74 | GPR119 (0.51) | GPR119GBA1KITGRM5GRM1 | |
| SCHEMBL30269885 | 0.74 | GPR119 (0.51) | GPR119GBA1KITGRM5GRM1 | |
| SCHEMBL16272002 | 0.74 | GRM1 (0.53) | GPR119GBA1KITGRM5GRM1 | |
| SCHEMBL24700150 | 0.73 | USP30 (0.43) | GPR119USP30UCHL1KDM4E | |
| SCHEMBL16271998 | 0.73 | GPR119 (0.47) | GPR119GBA1KITGRM5GRM1 | |
| SCHEMBL16272020 | 0.71 | KDM4E (0.51) | GPR119GBA1KITGRM5GRM1 | |
| SCHEMBL30502034 | 0.71 | GPR119 (0.47) | GPR119GBA1NAMPTKDM4EMEN1 | |
| SCHEMBL30213796 | 0.71 | GPR119 (0.47) | GPR119GBA1NAMPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279765-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-11-01 | — | — | CN | disclosed |