SCHEMBL29950860

SCHEMBL29950860

Cc1c(F)ccc2cc(C=O)[nH]c12

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
DAO P14920 2/20 0.38
ERN1 O75460 1/20 0.33
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20853126 1.00 CYP2A6 (0.41) CYP2A6DAOERN1AR
SCHEMBL26671161 0.82 CYP2A6 (0.43) CYP2A6DAO
SCHEMBL29955876 0.79 MAPT (0.46) CYP2A6DAO
SCHEMBL20853236 0.79 TNF (0.44) CYP2A6DAOAR
SCHEMBL4282939 0.75 DAO (0.53) CYP2A6DAOERN1AR
SCHEMBL22052047 0.74 HRH4 (0.43) CYP2A6ERN1
SCHEMBL2770272 0.72 CYP2A6 (0.42) CYP2A6DAOERN1
SCHEMBL4268467 0.72 CYP2A6 (0.38) CYP2A6DAOERN1
SCHEMBL5366835 0.71 DAO (0.53) CYP2A6DAO
SCHEMBL3599395 0.71 EIF4A3 (0.57) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed