Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26671161 | 0.82 | CYP2A6 (0.43) | CYP2A6ALDH1A1MEN1KMT2ADAO | |
| SCHEMBL26912475 | 0.82 | CYP2A6 (0.43) | MAPTCYP2A6ALDH1A1MEN1KMT2A | |
| SCHEMBL29950860 | 0.79 | CYP2A6 (0.41) | CYP2A6DAO | |
| SCHEMBL20853126 | 0.79 | CYP2A6 (0.41) | CYP2A6DAO | |
| SCHEMBL24970965 | 0.75 | MAPT (0.49) | MAPTALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31143052 | 0.75 | MAPT (0.49) | MAPTALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29954659 | 0.75 | HRH4 (0.44) | MAPTCYP2A6ALDH1A1MEN1KMT2A | |
| SCHEMBL20840621 | 0.75 | DAO (0.53) | MAPTCYP2A6ALDH1A1MEN1KMT2A | |
| SCHEMBL11712011 | 0.72 | MAPT (0.42) | MAPTCYP2A6ALDH1A1MEN1KMT2A | |
| SCHEMBL20853236 | 0.72 | TNF (0.44) | MAPTCYP2A6ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |