Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286093 | 0.78 | KDR (0.44) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL12787337 | 0.78 | ACACB (0.41) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL1285780 | 0.75 | ALDH1A1 (0.41) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL10187968 | 0.75 | ACACB (0.39) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL1285654 | 0.75 | ACACB (0.39) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL4064262 | 0.74 | ALDH1A1 (0.44) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL13384701 | 0.72 | ALDH1A1 (0.52) | PKMMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16435008 | 0.72 | ACACB (0.43) | ACACBPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL4064265 | 0.71 | ACACB (0.40) | ACACBMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3657536 | 0.69 | ALDH1A1 (0.43) | ACACBPKMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |