Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955284 | 0.84 | DHFR (0.38) | PDE4APDE4BPDE4CPDE4DUSP2 | |
| SCHEMBL2561011 | 0.82 | PDE4A (0.30) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2562728 | 0.81 | HTT (0.36) | PDE4APDE4BPDE4CPDE4DGLP1R | |
| SCHEMBL29956741 | 0.80 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL29958073 | 0.79 | SMN1; SMN2 (0.33) | GLP1RCDK4CCND1 | |
| SCHEMBL15331163 | 0.78 | SMN1; SMN2 (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29952980 | 0.77 | HTT (0.42) | — | |
| SCHEMBL15330703 | 0.77 | MAPT (0.40) | — | |
| SCHEMBL20578685 | 0.77 | NPSR1 (0.37) | PDE4APDE4BPDE4CPDE4DCDK4 | |
| SCHEMBL15330211 | 0.77 | KMT2A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |