Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30589401 | 0.78 | TDP1 (0.40) | ERN1TDP1ALDH1A1MEN1MAPT | |
| SCHEMBL1533918 | 0.78 | TDP1 (0.40) | ERN1TDP1ALDH1A1MEN1MAPT | |
| SCHEMBL29951690 | 0.75 | TDP1 (0.38) | ERN1TDP1ALDH1A1 | |
| SCHEMBL31723867 | 0.75 | TDP1 (0.38) | ERN1TDP1ALDH1A1LMNATRIM24 | |
| SCHEMBL660973 | 0.75 | TDP1 (0.38) | ERN1TDP1ALDH1A1LMNATRIM24 | |
| SCHEMBL29953875 | 0.75 | CYP1A2 (0.38) | ERN1TDP1ALDH1A1MEN1MAPT | |
| SCHEMBL15012943 | 0.75 | TDP1 (0.38) | ERN1TDP1ALDH1A1 | |
| SCHEMBL29952951 | 0.75 | ERN1 (0.44) | ERN1 | |
| SCHEMBL29956308 | 0.75 | ERN1 (0.43) | ERN1ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL29955820 | 0.74 | ERN1 (0.39) | ERN1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |