SCHEMBL29952951

SCHEMBL29952951

O=Cc1cc(O)ncc1F

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 15/20 0.44
KDM4E B2RXH2 1/20 0.33
ASPH Q12797 1/20 0.33
KDM8 Q8N371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24086588 0.78 ERN1 (0.38) ERN1KDM4EASPHKDM8
SCHEMBL412602 0.75 ERN1 (0.35) ERN1
SCHEMBL2213250 0.75 ERN1 (0.35) ERN1
SCHEMBL29951024 0.75 ERN1 (0.44) ERN1
SCHEMBL29954903 0.75 ERN1 (0.35) ERN1
SCHEMBL29952510 0.75 ALOX5AP (0.39) ERN1
SCHEMBL29956308 0.75 ERN1 (0.43) ERN1KDM4E
SCHEMBL29964486 0.75 ERN1 (0.35) ERN1
SCHEMBL12235269 0.75 KDM4E (0.59) ERN1KDM4EASPHKDM8
SCHEMBL29955820 0.74 ERN1 (0.39) ERN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed