Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | MTOR | P42345 | 6/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15696860 | 0.85 | KDM4E (0.44) | KDM4EPIK3CAMTORPIK3CBPIK3CD | |
| SCHEMBL15338074 | 0.77 | KDM4E (0.45) | KDM4EPIK3CAMTORPIK3CBPIK3CD | |
| SCHEMBL6936291 | 0.75 | KDM4E (0.55) | KDM4EPIK3CAMTORPIK3CBPIK3CD | |
| SCHEMBL29955721 | 0.74 | DHFR (0.38) | DHFR | |
| SCHEMBL15038356 | 0.73 | KDM4E (0.47) | KDM4EPIK3CAMTORPIK3CBPIK3CD | |
| SCHEMBL24456358 | 0.72 | RXFP1 (0.39) | KDM4EPIK3CAMTORPIK3R1DHFR | |
| SCHEMBL29956361 | 0.72 | RXFP1 (0.39) | KDM4EPIK3CAMTORPIK3R1DHFR | |
| SCHEMBL10202044 | 0.72 | KDM4E (0.45) | KDM4EPIK3CAMTORPIK3CBPIK3CD | |
| SCHEMBL29954016 | 0.72 | BACE1 (0.37) | KDM4E | |
| SCHEMBL2611051 | 0.72 | KDM4E (0.45) | KDM4EPIK3CAMTORPIK3CBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |