Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16332337 | 0.89 | MEN1 (0.59) | LIPEMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL13841458 | 0.83 | GRM5 (0.62) | GRM5MEN1KMT2ACYP1A2LMNA | |
| SCHEMBL1072784 | 0.83 | GRM5 (0.62) | GRM5MEN1KMT2ACYP1A2LMNA | |
| SCHEMBL2561397 | 0.82 | SMN1; SMN2 (0.48) | GRM5MAOBTSPOENPP2 | |
| SCHEMBL2504564 | 0.81 | MEN1 (0.47) | LIPEMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL29778401 | 0.81 | MRGPRX4 (0.51) | LIPEMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL2556339 | 0.81 | ENPP2 (0.60) | GRM5MAOBENPP2 | |
| SCHEMBL20371229 | 0.81 | MAOB (0.57) | LIPEMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL4516341 | 0.80 | CYP1A2 (0.58) | GRM5MEN1KMT2ACYP1A2LMNA | |
| SCHEMBL30994413 | 0.80 | CYP1A2 (0.58) | GRM5MEN1KMT2ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |