SCHEMBL29951072

SCHEMBL29951072

[C-]#[N+]c1ccc(Br)cc1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.42
AR P10275 15/20 0.38
HCAR1 Q9BXC0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12138270 0.78 IDO1 (0.42) AR
SCHEMBL12378214 0.76 GAA (0.55) AR
SCHEMBL9264759 0.76 GAA (0.55) AR
SCHEMBL6812746 0.76 KDM1A (0.39) KDM1AHCAR1
SCHEMBL6267032 0.73 KDM1A (0.50) KDM1AHCAR1
SCHEMBL2628176 0.72 DGAT1 (0.39) KDM1A
SCHEMBL12125524 0.72 AR (0.39) AR
SCHEMBL12340883 0.72 KDM1A (0.39) KDM1AHCAR1
SCHEMBL12340877 0.72 KDM1A (0.39) KDM1AHCAR1
SCHEMBL5574275 0.72 GLA (0.54) KDM1AHCAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed