SCHEMBL29951144

SCHEMBL29951144

NCc1cc(C=O)ccc1OC1CC1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.40
ALDH1A1 P00352 11/20 0.39
TSHR P16473 1/20 0.39
POLB P06746 2/20 0.38
CYP1A2 P05177 2/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
FDPS P14324 1/20 0.37
AOX1 Q06278 1/20 0.36
RXFP1 Q9HBX9 1/20 0.35
PDE4B Q07343 2/20 0.35
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957857 0.88 ALDH1A1 (0.40) CSNK2A1ALDH1A1TSHRPOLBMEN1
SCHEMBL25369123 0.80 HPGD (0.39) ALDH1A1TSHRPOLBCYP1A2MEN1
SCHEMBL25368648 0.79 HPGD (0.41) CSNK2A1POLBHPGDPDE4B
SCHEMBL29955342 0.79 ALDH1A1 (0.42) ALDH1A1TSHRPOLBHPGDFDPS
SCHEMBL29957120 0.79 ALDH1A1 (0.42) ALDH1A1TSHRPOLBHPGDFDPS
SCHEMBL23761321 0.76 SLC6A2 (0.44) CSNK2A1
SCHEMBL18519470 0.76 HPGD (0.51) CSNK2A1ALDH1A1TSHRCYP1A2HPGD
SCHEMBL4944263 0.75 ALDH1A1 (0.58) ALDH1A1TSHRPOLBHPGDKMT2A
SCHEMBL13522989 0.74 ALDH1A1 (0.68) ALDH1A1TSHRHPGDFDPSAOX1
SCHEMBL22713946 0.74 ALDH1A1 (0.68) ALDH1A1TSHRHPGDFDPSAOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed