Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2630762 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1POLBHTT | |
| SCHEMBL5871099 | 0.83 | CYP3A4 (0.42) | ALDH1A1SMN1; SMN2MAPK1POLBKMT2A | |
| SCHEMBL29882654 | 0.83 | CYP3A4 (0.42) | ALDH1A1SMN1; SMN2MAPK1POLBKMT2A | |
| SCHEMBL26084240 | 0.80 | KDM4E (0.40) | ALDH1A1SMN1; SMN2MAPK1POLBKMT2A | |
| SCHEMBL23049625 | 0.80 | POLB (0.46) | ALDH1A1SMN1; SMN2MAPK1POLBHTT | |
| SCHEMBL31353512 | 0.80 | POLB (0.42) | ALDH1A1SMN1; SMN2MAPK1POLBHTT | |
| SCHEMBL6160521 | 0.78 | CYP1A2 (0.38) | ALDH1A1SMN1; SMN2MAPK1POLBHTT | |
| SCHEMBL29951488 | 0.78 | CYP1A2 (0.38) | ALDH1A1SMN1; SMN2MAPK1POLBHTT | |
| SCHEMBL12057748 | 0.77 | MAPT (0.38) | ALDH1A1SMN1; SMN2MAPK1POLBKMT2A | |
| SCHEMBL11808695 | 0.75 | KDM4E (0.46) | ALDH1A1SMN1; SMN2MAPK1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |